Stretching along the southern side of Italy's Sorrentine Peninsula, the Amalfi coast dazzles with its mysterious grottos, craggy cliffs and shimmering bays. Grab a seat on the sea side of a regional bus to soak up views on the fabled route from artsy Positano to Amalfi. Ravello offers some respite from the crowds, plus the stunning Villa Cimbrone, which overlooks the Bay of Salerno. The historic section of Sorrento has winding streets filled with craftspeople. Capri is only a hydrofoil or ferry ride away.

Aix, a graceful, lively city, is known for its thermal hot springs, art schools and universities. Wander the Cours, old town and Quartier Mazarin on foot, stopping at cafés, bookstores and markets. Kids whining? Have them count fountains… Aix reportedly has 1,000 of them.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

The moody, romantic Scottish Highlands start at Loch Lomond just north of Glasgow. Comprising a slew of mountain ranges, this sparsely populated land is best seen by train on the West Highland Line. Mountains, lochs, bright heather and rhododendrons give way to white sand beaches and rugged coves as the train nears Mallaig. For a more active take on the region, hike the West Highland Way or visit the Trossachs National Park. Ben Nevis, a popular climbing spot, looms over the town of Fort William.

The landscape is dramatic—even a bit moody, with the Cuillin Range in the background—but outdoorsy kids will have a blast on the Isle of Skye. Plenty of water sports are available, and you’ll also find great hiking and even pony rides. Portree, the largest town, makes a great base for exploring this striking island.

Quebec City may be the only fortified city north of Mexico, but it welcomes visitors with open arms. Explore the Citadel, where you might catch Canadian troops staging a military ceremony. As for food, you could splurge on afternoon tea at the Chateau Frontenac, or do as the locals do and snack on poutine—french fries with gravy and cheese curds.

The Atlantic crashes on a coastline strewn with quaint harbors, windswept beaches, glorious dunes and blinking lighthouses. Explore Cape Cod National Seashore, bike past cranberry bogs on the Rail Trail or saunter around Sandwich, the Cape's oldest town. Many areas are architectural and culinary gems - full of weathered shingles, whaling captains' mansions, chowder shacks and upscale dining delights. Don't miss Woods Hole Oceanquest, famed Martha's Vineyard or charmingly upbeat Provincetown.