Built just to the east of the spectacular ruins of the capital of the Ayutthaya kingdom, a Siamese power destroyed by Burmese invasion in the 18th century, Ayutthaya is a modern Thai city studded with archeological wonders. Headless Buddhas and crumbling but still-beautiful reliquary towers and wats give evidence of the majesty of the civilization that was once centered here.

A visit to Pattaya is a wonderful way to explore the beaches along the Gulf of Thailand. Relaxed and family-friendly Jomtien Beach is a hot spot for watersports and seaside massages. The giant Buddha of Wat Khao Phra Bat keeps watch over the city, and the wooden Wang Boran Sanctuary of Truth pays homage to Buddhist and Hindu art and architecture. At night, tons of bars and strip clubs attract an adults-only crowd.

Kanchanaburi, capital of Kanchanaburi Province, is home to the Burma Railway (aka "Death Railway") bridge built by Allied POWs during WWII and immortalized in Bridge Over the River Kwai. A memorial and two museums commemorate those who died in the effort, and a yearly carnival includes a pyrotechnic recreation of the bridge’s bombing. The wider province offers forests and caves to explore, and beautiful waterfalls.

The Singapore cityscape looks like it was ripped from the pages of a science fiction comic book. If you’re hungry for a true Singapore experience, sample the myriad street foods or take a cultural cooking class. The Botanic Gardens and the Gardens By the Bay offer a slice of horticultural heaven, and the observation deck of the Sands SkyPark makes you feel like you’re high above the clouds. The banks and walkways along the Singapore River bustle with local activity.

Packed with historic landmarks, bustling eateries, and manicured parks, the vibrant city of Lahore exudes culture at every corner. From soaring minarets and colorful facades to street-level stalls selling flavorful Punjabi favorites, the increasingly cosmopolitan city radiates with energy.

Serving as the capital of Pakistan since the Sixties, Islamabad was built according to a carefully organized plan, divided into sectors along a grid of clean, tree-lined streets. The city is sheltered by the Margalla Hills, the foothills of the Himalayas and the home of rare species of leopard, deer, birds, and even porcupines. Several hiking paths end at Daman-e-Koh, a picnic spot with a splendid view of the entire city, including the massive modernist Faisal Mosque and even the Rawal Dam.

Tradition collides with pop culture in Tokyo, where you can reverently wander ancient temples before rocking out at a karaoke bar. Wake up before the sun to catch the lively fish auction at the Toyosu Market, then refresh with a walk beneath the cherry blossom trees that line the Sumida River. Spend some time in the beautiful East Gardens of the Imperial Palace, then brush up on your Japanese history at the Edo-Tokyo Museum. Don’t forget to eat as much sushi, udon noodles, and wagashi (Japanese sweets) as your belly can handle.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Known as the safari capital of Africa, Nairobi is an energetic, modern city that serves as a fascinating introduction to both wildlife and nightlife. Music clubs pulse with life, shops and markets bustle, and a mélange of restaurants will tempt your palate in this former Maasai watering hole. Top sights include the Karen Blixen Museum, Giraffe Centre and the black rhinos of Nairobi National Park. The compact city center is safe to walk in and taxis make other areas accessible.