Located at the entrance to the Great Smoky Mountains National Park, Cherokee is the headquarters for the Eastern Band of Cherokee Indians. Signs around town are in English and Cherokee, and the city itself is anchored by the Harrah's Cherokee Casino. The tourist-oriented area is rich in outdoor activities for the entire family. The tribe runs a botanical garden, cultural museum, Indian village recreation, historical dramas, and an arts and crafts center.

Greenville, South Carolina, is anchored by what Forbes Magazine calls one of America's Best Downtowns. Featuring a one-of-a-kind "floating" suspension bridge and set against the scenic Blue Ridge Mountains, Greenville boasts a thriving arts scene, hundreds of restaurants, shops and boutiques, popular annual festivals, numerous historic sites and museums housing significant art collections. Excellent interstate service and a user-friendly international airport make access easy.

Gatlinburg, at the heart of Great Smoky Mountains National Park, is an ideal base for a family looking to explore the park's numerous offerings. After you've gone hiking, fishing, rafting or horseback riding, ride an elevator 342 feet to the top of the Gatlinburg Space Needle for stunning views of the Smokies. There's also an amusement center next door with nifty rides and games.

Set against the misty blue backdrop of the Great Smoky Mountains National Park, Pigeon Forge, Tennessee is a gateway to 500 thousand acres of Appalachian wilderness. If hiking over 800 miles of mountain trails and camping in dense ancient forests isn't your thing, head over to Dollywood for a different sort of fun. Founded by country queen, Dolly Parton, Dollywood combines rollercoasters, waterslides, and live bluegrass and gospel concerts, with a down home country fair.

Sevierville Tennessee is located on the eastern edge of the state, the town sits in the foothills of the Great Smokey Mountains, about ten miles north of the park. There are plenty of outdoor activities such as horseback riding and the Forbidden Caverns for the kids. Additionally, this quaint and quiet town's claim to fame is as the birthplace of Dolly Parton as well as being home to outlet malls and restaurants out on the highway.   

Named "the only place in the world where snow falls upside down" by Ripley's-Believe-It-Or-Not, the legendary Blowing Rock geological formation has been attracting visitors to its corner of North Carolina since 1933. The accompanying mountain village of Blowing Rock sits 4,000 feet above sea level along the scenic Blue Ridge Parkway. The winter brings enough snow to the nearby Blue Ridge Mountain peaks that it is possible to ski the south, staying over at one of Blowing Rocks charming B&Bs.

Named for legendary explorer, Daniel Boone, Boone, North Carolina retains the pioneer spirit, despite having grown into a busy college town, the home of Appalachian State University. The surrounding area is one of the country's best destinations for outdoor adventures. Walk across the Mile High Swinging Bridge to Grandfather Mountain's Linville Peak, the highest point in the Blue Ridge Mountains, or grab your bike and head to Pisgah National Forest, featuring over 200 miles of exciting trails.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

The windy city is a cornucopia of modern art, fine dining, cutting edge comedy, and die-hard sports fans. Snap a photo of your reflection in the silver Cloud Gate sculpture at Millennium Park before heading to Grant Park to get hit with the refreshing spray of Buckingham Fountain. There are dozens of museums and theater companies in Chicago, so a cultural experience is never hard to find. You’re sure to laugh your head off at the Second City Theater, the professional launch pad of many famous comedians.

Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

New Orleans is full of life—but with a laid-back energy that sets it apart from other cities. You’ll wanna soak it all in: impromptu jazz performances up and down Frenchmen Street, the ding of the St. Charles Streetcar, moss-draped trees in the famous Garden District…even its gothic, above-ground cemeteries. (The city’s said to be one of the most haunted in America.) For some, NOLA will always be all about Bourbon Street, but for travelers looking to take it slow, the city’s distinct blend of cultures—including Creole and Cajun—means there’s tons to see, explore, and yes, eat.

Walk the Freedom Trail the first time you visit Boston and you'll quickly get a sense of this coastal city's revolutionary spirit and history. But make sure you also explore some of Boston's fine museums (try the Isabella Stewart Gardner, featuring masterpieces displayed in their collector's mansion) and old neighborhoods (like the North End, Boston's Little Italy). You can't claim to have experienced real Boston culture, though, until you've watched a Red Sox game from the bleachers.

Have you ever wanted to experience elevated city life? Then step on up to The Mile High City! Denver gives you the best of both worlds with mountain adventures and city excitement. Access to the majestic Rocky Mountains is a breeze and only an hour drive away, making Denver your perfect basecamp. During your stay, check out the award-winning dining scene with 26 Michelin-rated restaurants that will have you dining like a star. But, the fun doesn’t stop there! With a thriving and diverse arts and culture scene, live music at bucket-list concert venues, and championship level professional sports, you can truly do it all in Denver. Elevate your next getaway, and find Mile High City recommendations below!

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

Hollywood beckons to tourists who long for a brush with Tinseltown glamor. Tour movie studios, slip your hands into the famous prints at the TCL Chinese Theatre, or indulge in a celeb sighting at one of LA’s white-hot nightspots. Spot your favorite star while shopping at The Grove, or forget all about the famous eye candy as you take in the iconic artwork at The Getty Center. For a different type of star-gazing, peek through the telescopes at the Griffith Observatory.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Lingering over pain au chocolat in a sidewalk café, relaxing after a day of strolling along the Seine and marveling at icons like the Eiffel Tower and the Arc de Triomphe… the perfect Paris experience combines leisure and liveliness with enough time to savor both an exquisite meal and exhibits at the Louvre. Awaken your spirit at Notre Dame, bargain hunt at the Marché aux Puces de Montreuil or for goodies at the Marché Biologique Raspail, then cap it all off with a risqué show at the Moulin Rouge.