Stay Smart at the Holiday Inn Express Hotel in the Greater LaCrosse Area. Whether corporate or leisure travel brings you to our premiere location, our friendly and professional associates are sure to make you feel appreciated and welcome. The hotel is located just minutes from the Mississippi River, historic downtown LaCrosse and UW LaCrosse. Begin your day with our Express Start Breakfast Bar featuring our signature hot cinnamon rolls, and hot breakfast items such as scrambled eggs, sausage, bacon and biscuits with gravy. All of this plus fresh brewed Smart Roast coffee, juice, cold cereal, yogurt and bagels .Our newly renovated hotel features spacious, contemporary guest rooms with complimentary high speed wireless Internet access and local phone calls. Work out in our fitness center or relax in our heated indoor swimming pool and whirlpool. The Holiday Inn Express Hotel, Onalaska is located across the street (walking distance) from TGI Fridays, all guests receive a 15% discount with room key. For those who prefer to relax and dine in, Room Service is available from TGI Friday's Nightly 5pm-10pm On site meeting accommodations for up to 40 people. Stay 'smart' when you stay at the Holiday Inn Express Hotel. Pet Friendly Hotel!