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Main Street Inn B&B

Traveler (33)
Room & Suite (5)
Dining (1)
221 N Main St, Sainte Genevieve, MO 63670-1339 See on map
Free Wifi
Free Parking
Breakfast included
Air Conditioning
Non-Smoking Hotel
Family Rooms
Reviews (68)
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All reviews the main street st louis breakfast was excellent house is beautiful room was spacious second floor porch hosts books perfection
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1 - 5 of 68 reviews
Reviewed 4 days ago via mobile

Perfect B&B experience! This house is so beautiful and the rooms are exceptionally clean and comfortable! We were greeted by a sweet lady named Clemmy who made us feel very welcome! She set us up with wine and a cheese plate that we enjoyed on...More

Thank Kimberlou
Reviewed 2 weeks ago via mobile

This B&B was truly delightful! My mom and I planned a last minute trip for the weekend to visit the nearby wineries and we were surpirsed to have found an open room. Prior to arriving, my mother called and spoke to the inn manager about...More

Thank olk8455
Reviewed 3 weeks ago via mobile

This was our second visit and my husband and I are sure to be regulars. This is beautifully updated, peaceful B&B with delicious food and engaging nightly wine and cheese socials. We love it here and are already looking forward to hearing back next year.

Thank Jcamille30
Reviewed 5 weeks ago

My husband and I had a great time in St. Genevieve. The Inn was remolded beautifully, the room was comfortable even down to the super soft toilet paper. The Inn keeper was very friendly shared lots of history about the down. Breakfast was delicious and...More

Thank Excursion714731
Reviewed August 22, 2018 via mobile

The 7 of us were traveling together and this was the second night of our 3 week road trip. What a fantastic experience!! We range in ages from 7 to 70 and all loved it. The rooms are beautiful, unique, and very comfortable and clean....More

Thank Escape745783
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Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been considered one of Missouri’s finest bed and breakfast establishments. Having recently undergone an extensive year-long More renovation, Proprietors, Susan O’Donnell and Patrick Fahey, along with Innkeeper, Jean Marie Rozier Sellberg, are thrilled to re-open the Main Street Inn B&B and provide a truly wonderful experience. Located in the heart of Sainte Genevieve’s Historic District, and surrounded by beautiful wine country, we are just a short one-hour drive from both St. Louis and Cape Girardeau, five hours from Chicago and just a little over four hours from Nashville. If you are looking for a relaxing and peaceful getaway, the Main Street Inn B&B is the perfect destination. Less
Hotel Amenities
Free Parking
Free High Speed Internet (WiFi)
Breakfast included
Air Conditioning
Non-Smoking Hotel
Room Service
Fitness Center with Gym / Workout Room
Room types
Non-Smoking Rooms, Family Rooms
Room types
Non-Smoking Rooms, Family Rooms
Number of rooms
United States > Missouri > Sainte Genevieve
Room types
Non-Smoking Rooms, Family Rooms
Number of rooms
United States > Missouri > Sainte Genevieve
Traveler (33)
Room & Suite (5)
Dining (1)
Business Center & Event Rooms (3)
Nearby HotelsSee all 3 nearby hotels
Hotel Ste. Genevieve
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Microtel Inn & Suites by Wyndham Sainte Genevieve
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Best Western Chester Hotel
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13.50 miles away
Red Bud Country Inn
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15.01 miles away
Nearby RestaurantsSee all 29 nearby restaurants
Anvil Restaurant & Saloon
234 reviews
.25 miles away
Hotel Audubon's Grill & Bar
154 reviews
.14 miles away
Stella and Me
67 reviews
.02 miles away
85 reviews
.21 miles away
Nearby AttractionsSee all 28 nearby attractions
Ste. Genevieve Welcome Center
61 reviews
.22 miles away
Felix Valle House State Historic Site
39 reviews
.18 miles away
Bolduc House Museum
44 reviews
.26 miles away
Sainte Genevieve Catholic Parish
14 reviews
.29 miles away
Questions & Answers
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Room Tips
"Stay up top for a better view or in the rendezvous or the room off of the porch"
Aug 16, 2018
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"We liked the Audubon room"
Aug 14, 2018
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"I looked at the rooms and everyone of them was beautiful."
Aug 13, 2018
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"make sure your floors don't squeek"
Jun 5, 2018
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