Welcome to the Holiday Inn Express Hotel & Suites Daphne, located just minutes from Mobile, AL and a short drive to Pensacola, FL. Travelers appreciate how our location makes Stay Smart a Daphne hotel reality. We are located on I-10, the main interstate connecting the East Coast & West Coast, at exit 38. Shopping is at it s finest just across the street at the newest regional mall, the Eastern Shore Center. Featured stores include Sharper Image, Pottery Barn, Dillard s and Williams Sonoma, as well as many choices for casual and upscale dining. Play golf between business appointments at Timber Creek, a 27 hole public course, adjacent to the hotel.Relieve stress by exercising in our fitness center, or swim and relax at our outdoor pool. If you require Group Meeting facilities we can accommodate up to 75 people. High Speed Internet Access is available in our lobby, business center, and all guest rooms. Start the morning off right with our complimentary Express Start breakfast.Businesses near hotel: Mercy Medical, Symphony Health Services and coming soon the Daphne Commerce & Technology Center.Attractions near hotel: Battleship USS Alabama, Mobile River Delta Excursions, United States Sports Academy and Timber Creek Golf Course. For business or pleasure Stay Smart at the Holiday Inn Hotel & Suites, Daphne, Alabama.