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Your one-stop shop for finding the best flights from Louisville to Sioux Falls. Simply tell us where and when you want to travel and we'll do all the legwork for you. Featuring the most powerful shopping tools on the web, we search the largest online travel websites, established airfare discounters, plus the world's leading airlines and low-cost carriers to bring back thousands of flight options.

Travel information for Louisville, KY to Sioux Falls

Route information
  • Louisville, KY is 684 miles from Sioux Falls
  • Chicago, IL - O'Hare International Airport is the most popular connection for one stop flights between Louisville, KY and Sioux Falls
Arrival information
  • Sioux Falls Regional Airport (Jo Foss Field) (Sioux Falls, SD)
    • Right now, 14 airlines operate out of Sioux Falls Regional Airport (Jo Foss Field).
    • Sioux Falls Regional Airport (Jo Foss Field) offers nonstop flights to 11 cities.
    • Every week, at least 357 domestic flights and 0 international flights depart from Sioux Falls Regional Airport (Jo Foss Field).
Several popular airlines fly into Sioux Falls Regional Airport (Jo Foss Field), including

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