I believe most people who visit this fascinating city for the first time will most definitely visit districts such as the New Town,Old Town, Lesser Town, Castle District and why not ,amazing architecture and amazing pubs, bars, cafe's and restaurants but some of the other districts in this city although not as pretty are most certainly as interesting, one such district is the Zizkov district.
This is more a working class area ,landmark feature here is obviously the famous Zizkov Tower,architecture here is good and the nightlife scene superb, there's so many great pubs,bars, cafe's and restaurants in this district which is a more authentic sense of what this city is all about ,I love it here ,to reach this district is easy, its a short train. bus or metro ride ,its most definitely well worth checking out if you're planning a holiday to Prague.