Dear Judy, I suppose you refer to the Palazzo Venezia museum which is located in San Marco square just next to Piazza Venezia. As per their website, the museum is open Tuesdays through Sundays 8.30am to 7.30pm with last entrance at 6.30pm. Enjoy your stay in Rome!

First of all, you can easily spend five days in Rome without even having scratched the surface of it. There is so much to see and do and so much to be impressed by - if I were you I would definitely consider spending the time in Rome only (this includes the surrounding area, e.g. Ostia Antica). That being said, if you wish to discover other cities Florence is definitely a good bet, as it is easily reachable from Rome. The best option is the Frecciarossa bullet train which takes about 90 mins to get you from Rome to Florence. A regular return ticket will set you back about 50,- Euros ("Standard"=Coach class), but there are plenty of discount options, especially when you buy in advance. Check out the Trenitalia web site for further info. Also, trains run very frequently (there should be a service about every 30 mins.) Florence is also a good option in terms of things to be seen - it's essentially the capital of Renaissance Italy (which is a nice contrast to Rome). On the downside, Florence tends to be quite crowded, too. A good alternative in Tuscany is Siena which, however, takes much more time to reach from Rome. I would not recommend going to Pisa. Except for the leaning tower there is not much to see that you wouldn't be able to see otherwise either. It's not worth taking the 3h (one way) train ride from Rome. If you want to head further north, Bologna might be an interesting option. It gives you a nice impression of the Emilia Romagna region which - as you will see - is very much different from Roma and Latium. The trip to Bologna on a frecciarossa or frecciargento train will take about 2-2 1/4 hours and cost about 60,- Euros for a regular return ticket in coach class. Towards the south, a destination to consider is Naples from which you can easily get to the Pompeii excavation sites, take a boat trip to Capri with the blue grotto and much more. As for transport it is about the same as for going from Rome to Florence (travel time is shorter with just above an hour). I hope this is helpful info to you. Enjoy your stay in Italy - it's a great place!