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Cape Girardeau Hotel + Air Packages

View of the Mississippi River at Trail of Tears State Park
Historic Downtown Cape Girardeau
Mississippi River Tales Mural
Build your own Cape Girardeau vacation package
Want to book a vacation to Cape Girardeau? Whether you're off for a romantic vacation, family trip, or an all-inclusive holiday, Cape Girardeau vacation packages on TripAdvisor make planning your trip simple and affordable.
Find the perfect vacation package for Cape Girardeau on TripAdvisor by comparing Cape Girardeau hotel and flight prices. Travelers like you have written 888 reviews and posted 388 candid photos for Cape Girardeau hotels. Book your Cape Girardeau vacation today!
Holiday Inn Express Cape Girardeau
#1 Hotel in Cape Girardeau
Holiday Inn Express Cape Girardeau
We stayed here two nights with our daughter and two grandchildren and had adjoining, connected rooms, which were quite nice. Our room's bathroom was equipped with grab bars in tub...
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Auburn Place Hotel & Suites
#2 Hotel in Cape Girardeau
Auburn Place Hotel & Suites
“Comfy beds” 07/09/2014
Staff is genuinely welcoming and friendly. Property is clean and well maintained. Very comfy beds, huge improvement over the previous beds before the remodel. Breakfast isn't...
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Drury Suites Cape Girardeau
#3 Hotel in Cape Girardeau
Drury Suites Cape Girardeau
Our daughter is a student athlete at SEMO so we're frequently in Cape Girardeau to watch her compete, etc. We always stay in a suite at the Drury Suites--you get a nice two room...
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2. Find the right flight
Cheap Flights to Cape Girardeau
All Washington to Saint Louis (WAS-STL) fares found by travelers in the past 72 hours*
Jul
$257 round trip
Aug
$252 round trip
Sep
$118 round trip
†  Prices are based on round trip travel with returns between 1-21 days after departure. These are the best fares found by travelers who searched TripAdvisor and a select group of our fare search partners in the past 72 hours. Ticket prices and seat availability change rapidly and cannot be guaranteed.