Outside the Vatican wall 100 meters above the Musei Vaticani <Sistine Chapel entrance>, nice location with easy access to Cipro Metro. You can walk down the road (Vialle Vaticano) 1/2 mile, or take the steps (80) down to Via Angelo Emo for supermarket Conrad, dry cleaners, metro etc. La Fornace on Angelo Emo is nice local place. Most "central" places and restaurants are €12 taxi ride away. Local taxis respond quickly and easily with provided numbers.
Gianni checks you in and out easily and helpfully.