The crown jewels, Buckingham Palace, Camden Market… In London, history collides with art, fashion, food, and good British ale. A perfect day is different for everyone: culture hounds should hit the Tate Modern and the Royal Opera House. Clotheshorses will drool over Oxford Street shops. For foodies, cream tea at Harrod’s or crispy fish from a proper chippy offers classic London flavor. Music and book buffs will freak out over Abbey Road and the Sherlock Holmes Museum (at 221B Baker Street, natch).

Famed for its soccer team and music scene, which has produced the likes of the Smiths and Oasis, this center for sports and the arts is a down-to-earth and friendly city. The so-called Capital of the North has overcome industrial decline, bombing (in WWII and by the IRA) to become a confident and cosmopolitan city of well over two million. It is well served by a bus and light rail network. Top attractions include the Lowry art complex, arcade Affleck's Palace and Canal Street gay village.

Scotland's largest city is a friendly, bustling town with imposing 19th-century buildings, vibrant theater life, the most talked-about independent music scene outside the U.S. and watering holes that run the gamut from trendy bars to traditional pubs. The city's buses and subway system make it easy to explore. Don't miss the reopened Kelvingrove Art Museum, the Victorian Necropolis, or the surprisingly delicious local delicacy: deep-fried pizza. Glasgow is the gateway to the Highlands and Islands.

Liverpool's fortunes have historically been tied to shipping. But imports and exports like sugar, spice and tobacco pale in comparison with Liverpool's most famous export of all—the Beatles. Relive the hysteria at the Beatles Story Experience, and check out Paul's childhood home, but also leave time for exploring Liverpool Cathedral and the Walker Art Gallery.

With a population of almost 300,000 in the city proper, Belfast has grown into a cosmopolitan destination and become a popular weekend break spot. With feelings of optimism and life pulsing through the city, Belfast makes for an energizing getaway. It's never been easier to tour the city, thanks to a number of intriguing bus, taxi, boat and pedestrian options. Don't miss the Ulster Folk Museum or the Belfast Cathedral, and make sure to experience some of the award-winning restaurants, bars, clubs, galleries and theaters.

The UK’s favorite holiday resort continues to attract millions of visitors. Families and couples, young and old, Blackpool’s unique appeal is that it appeals to everyone. Whether you’re looking for thrills and excitement, family entertainment and historic gems or beautiful gardens and stunning beaches, Blackpool has it all. Blackpool Pleasure Beach, Sandcastle Waterpark, Blackpool Zoo, the Blackpool Tower, the Illuminations and a packed year-round events calendar all add to the charms of this seaside spot.

The geographical heart of England, Birmingham started life as a sixth- century Anglo-Saxon village. Today, much of this city of over a million dates back to post-WWII redevelopment in the 1950s and 60s. Cutting edge museums and galleries, innovative theaters and excellent shopping have contributed to Birmingham's appeal as a weekend break destination. Don't miss the Balti Triangle, home to the Pakistani food in the UK, the hopping bars and cafes of Gas Street Basin, or the National Sea Life Centre.

Mild ocean breezes, sandy beaches and swaying Torbay Palms give the small English town of Torquay a distinctively Mediterranean feel. More than just a beach spot, Torquay boasts an enormous coastal aviary and the famous Kents Cavern Prehistoric Caves. Agatha Christie spent most of her life here, and the city is now home to multiple film companies. With such a rich literary history, Torquay may be the perfect place to finish writing that novel or screenplay, or just to relax with a good mystery.

Walk or take the tram to the summit of the Great Orme—you’ll be rewarded with a splendid view of Llandudno, a popular seaside resort in Wales. (Just take a jacket. It can be chilly up there.) On your way up, stop at the Great Orme Copper Mine for a fascinating look at how copper was mined 3,000 years ago.

Bristol is a quirky British city with beautiful hilly vistas and plenty of historic sights to explore. Anyone interested in ships will have a blast aboard Brunel’s SS Great Britain, the world’s first great oceanliner, and the Matthew, a replica of the ship upon which John Cabot sailed to America in the 15th century. The graceful Clifton Suspension Bridge is another must-see.