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Whether by plane, train, or automobile, there's a way for you to get to Kalamazoo.
The Kalamazoo/Battle Creek International Airport is the airport that serves the Kalamazoo area. Most major airlines provide service to the airport, including United, Delta, American, and Continental, among others. Direct service is provided to the airport from cities including Chicago, Detroit, Atlanta, Cincinnati, and Minneapolis. You can pick up a rental car from the airport; service desks in the arrivals terminal include Avis, Budget, Enterprise, Hertz, and National/Alamo.
Amtrak provides service to the city. The train ride from Chicago to Kalamazoo takes about 2 hours. The Amtrak station is located at 459 N Burdick Street.
Aside from the requisite highway construction, traveling to K-town by car is not that too taxing. Kalamazoo is lcoated off of Interstate 94. If traveling north from Indianapolis, you can get to Kalamazoo by taking Interstate 69 to I-94. The Greyhound station is located at the same place as the Amtrak station; 459 N Burdick Street.