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Valdosta is located along Interstate 75 in south Georgia. The main exits for Valdosta are 16 and 18. Exit 22 serves the northern portion of the city. Major cities nearby are Macon, GA (2.5 hrs N); Tallahassee, FL (1.5 hrs W); and Jacksonville, FL (2 hrs E).
Valdosta is served by Valdosta Regional Airport (VLD), which has two flights daily from Atlanta. The closest major airport is Jacksonville (JAX), around 2 hours east of Valdosta. There are no flights between Jacksonville and Valdosta.