There is lively nightlife to be found in Arequipa, primarily around the old quarter. Locals and tourists party in the bars, discos, and restaurants on Thursday, Friday, and Saturday nights. These establishments are open during the week, the mood is much more subdued.

For live music, check out Las Quenas on Santa Catalina. This pena bar and restaurant has live Andean music every night during the week, and dance performances on the weekend nights. Many tourists head to La Troica on Jerusalen for folk music, or El Tuturutu on Portal San Agustin for more pena music.

Things are more lively times at La Lena at Zela 202, a pub with plenty of drinks and music, and Siwara on Santa Catalina, a beer tavern that features two patios in the building of the Santuarios Andinos museum. The Montreal Le Café Art on 300B Santa Catalina is another hot spot, with live music and happy hours.

You can step it up even a notch further at Forum Rock Café at 317 San Francisco , a huge establishment with a restaurant, concert hall, bar and disco. Within the rainforest theme are canopy walkways, live rock bands, and a second-floor scenic view of the city. Kibosh at 205 Zela offers a live music and a dance floor, with four bars, and at 319 San Francisco , Déjà Vu is popular with locals and tourists alike, thanks to its hopping dance floor, rooftop terrace, and English-language movies on a big screen.