CAMPO DE' FIORI
This is a lively square in central Rome that starts each morning as a market place and ends as a popular drinking spot.  During the mornings from Monday through Saturday, there is a fruit and vegetable market which, while expensive, sells the best-tasting, sun-ripened fruit around!  

By early afternoon, the stalls are pulled down and from then on, it's a fantastic place to get a drink and sit in the sun. The cheapest drinks are sold as "takeaway" where you can enjoy your glass of wine while standing in the square. However, it's not too expensive to get a wonderful seat at Vinearia and enjoy the people-watching and the street performers from a comfortable spot. This place is very crowded on weekend evenings, and a lot of foreigners gather there, above all young people. Be careful because somebody can have a bit too much alcohol and glasses (now only plastic) may fly!

Wind through a maze of streets to the north to reach piazza Navona, a wide open space that used to hold chariot races in ancient Roman times. While it is very touristy, it is a Baroque masterpiece with fountains designed by Bernini well worth seeing. There are several restaurants to choose from however the Romans encourage tourists looking for "real" Italian food to look elsewhere. Here you will also find a slew of caricature artists along with the usual array of vendors and souvenir stands geared towards tourists. 

Renovation work on the spectacular Fontana dei Quattro Fiumi in the centre has now been completed. 

TRASTEVERE
A really lovely part of Rome, which is across the river from Campo de' Fiori; its centre is piazza di Santa Maria in Trastevere and there are narrow cobbled streets, ivy covered buildings, and plenty of bars and restaurants going from there. There are a few beautiful churches, including Santa Maria in Trastevere and Santa Cecilia.  It is very crowded on the weekends, so don't try to reach it by car! It will save your feet a lot of trouble to take the #8 tram from the Roma Trastevere train station (trains from Fiumicino airport stop there every 30 minutes) or from across the river in central Rome.

ESQUILINO (Termini station)
The area around the main train station may seem seedy to a visitor and has mainly tourist hotels and bad tourist food. For a more authentic Roman experience, avoid eating near the station if possible.  It is inevitable that you will be approached by guides selling various tourist bus services; do not be intimidated into choosing the first offer.  Some of the bus tours only go to a few of the key sites, while others are quite comprehensive and give you a good introduction to Rome's layout and how to get around it.  Even if you can't take in all the sights during the bus tour, you can walk around without getting lost!

Form Termini train station it is easy to reach the centre of Rome where most of the sightseeing locations are: both Metro lines (A and B) have a stop below the station, and a huge bus terminus is located right in front of it.

EUR
EUR is a suburban residential area and a business district. The heart of EUR was built in the late '30s, at Mussolini's request, for the Esposizione Universale (World Fair) of 1942 (which never took place); the area was completed in the '50s and today, the neighbourhood serves as Rome's financial district. The EUR is very different from what one sees in the historic center of Rome: there are no ancient Roman ruins or quaint spots in this area and the streets are wide and modern. It's a well-balanced area with concrete and glass highrises surrounded by wide green areas and trees. You will find both buildings and villa-type constructions in separate places.

The Palalottomatica is a popular venue for concerts and other events (it can also serve as a stadium); also, there's an artificial lake in the EUR that the Romans call laghetto (pronounced: la-ge-to) meaning "little lake" - it is surrounded by a Japanese garden / park that can be pleasant to walk through and there are some places to eat and have ice cream around the lake. Avoid the lake on weekends if you are lookng for peace and quiet; the place will be packed with families and kids. EUR is also where Rome's theme park was based. The theme park in question, called "LUNEUR", was nothing compared to most theme parks like Disney due to its small size and limited type and number of attractions (it closed in 2008).

The neighbourhood also hosts some interesting (and surprisingly quiet) museums: the Museo della Civiltà Romana (Museum of the Roman Civilisation, has lots of casts of ancient sculptures and a famous plastic of Imperial Rome), the Museo Etnografico L. Pigorini (this ethnographic museum hosts a most interesting collection of African artefacts from Italy's former colonies and other objects from the various peoples of Oceania) and the Museo delle Arti e Tradizioni Popolari, showcasing folkoristic dresses and various tools from the regions of Italy. Other popular landmarks in the area are the Palazzo della Civiltà Italiana (also known as the "Square Colosseum") and the imposing St. Peter and Paul's basilica.

EUR is connected to the city by both Metro (line B, stops: "Eur Fermi", "Eur Palasport") and bus transportation; the former is the fastest and easiest way to get to and from it. There is presently a lot of construction going on; an aquarium - and Massimiliano Fuksas' "Nuvola" ("Cloud"), are currently under construction. Works take place during the week, with huge bulldozers - that might spoil your peace and quiet!

If you are a tourist who wants to be as close as possible to the major sight-seeing areas, this would not be the best location to stay while visiting Rome; in this case, it would be etter to spend a couple dollars more but be as near to the center as possible; while staying in the city center you will save on transportation since you will be able to move among most of the sight-seeing locations by foot as the majority of them is close to each other. However - If you think that Rome is not only about seeing places, but is also about living them and strolling around like a Roman, the EUR is one of the places to be. 

TESTACCIO and OSTIENSE

They're Rome's traditional working-class districts; night clubs and discos are still popular but less than in the '70s-'80s. The neighborhoods to go to for this kind of entertainment are Testaccio and Ostiense; Testaccio is a very good place for traditional food, too. Shhh, don't tell everybody, it won't last long.

PRATI (Vatican Area)

Prati - with its wide streets, tree-lined boulevards and leafy squares - differs greatly from the city centre. It was built immediately after the annexation of Rome (1870) in order to house the civil servants of the newly formed Kingdom of Italy. Despite it being very close to St. Peter's, the city planners designed its layout in such a way to make impossible for anybody to see the basilica's dome (the Kingdom of Italy and the Pope had bad - if non-existent - diplomatic relations at the time). This district is well-served by the A line of the Metro (with the "Ottaviano - San Pietro - Musei Vaticani" and "Lepanto" stops), by various bus lines and by the #19 tram route.

Also, the Vatican Museums are located nearby.

This neighbourhood offers a great deal of b&bs and hotels, with varying categories and prices; the main boulevard is via Cola di Rienzo, which is also one of the city's most prominent shopping areas. If you're looking for good food, Castroni and Franchi are the places to go, while two of Rome's finest gelaterie are located here: Gelarmony (on via Marcantonio Colonna) and the Gelateria dei Gracchi. If, on the other hand, all you're looking for is clothing, the COIN department store - with the several fashion boutiques located along the boulevard - is what you need.

Safety in Neighbourhoods

Safety is not a big issue when talking of violent crime but in all central neighbourhoods, particularly near Termini, beware of pickpockets and scammers. Use your common sense as you would in any other big touristy town, paying attention to your surroundings on public transport and in crowded areas.