The largest airport around is the Nice-Côte d'Azur airport just outside of Nice, located about 20 miles (30 km) away. This is the second most important (in terms of volume of traffic and international destinations served) airport in France after Charles de Gaulle in Paris. The two terminals here serve almost every major airline in Europe. It is possible to get to almost every sizable city in Western Europe from Nice, and many of the larger Central and Eastern European cities are also served by Nice (including Warsaw, St. Petersburg and Budapest) . As one of the southernmost points in France, it is also a gateway to Mediterranean and African destinations. Flights to Middle Eastern and Arab nations are particularly frequent. Flights to destinations such as Dubai, Istanbul, Beirut, Casablanca, Algiers and Tunis can all be easily found. Flights from the Americas or Asia are much harder to come by, though Delta does fly directly from New York.

For those who wish to drive, Menton is located just off a major road, A8/E74/E80, which runs along the Mediterranean coast and threads through Monaco, Nice, and into Aix-de-Provence, where Marseille is located. Going the other way, the route leads into Italy and becomes the Autostrada Azzurra. The drive from Nice is about 30 minutes. Getting to Menton from Genoa (the closest large Italian city) takes about two and a half hours.

There are several car rental agencies with counters at the Nice airport, including Avis, Budget, Europcar, Hertz and Sixt. Due to the large size of the airport, there are usually two offices, one for each terminal. Call the office in advance to reserve a car, especially during the summer, as vehicles are sure to go quickly.

RCA (Rapides Côte d'Azur) is a service that offers shuttles to and from the Nice Airport (line 110); between 9am and 9pm; price 30 euros (February 2015) if you buy a tur-retur ticket. If you buy one way only, it costs € 20.