Queen Street is as varied and eclectic as the neighbourhoods it passes though.  

From the east, with its parks and community feel, through the more urban  areas, past the Eaton Centre at Yonge Street, Old Toronto City Hall at Bay, New City Hall at York St, and on to the area that most people associate with Queen Street, Queen West. This area is often said to have a Soho-like feel.

Starting at Osgoode Station and University Avenue  (this intersection has a public transit station), you would make your way west past historic Campbell House on the northwest corner (tours available). Further along, you will begin to see boutique stores like the Condom Shack and a store of everything hemp, The Friendly Stranger. There are also restaurants like Nota Bene, Little India, a variety of pubs, and the Korean Grill House. If you get hungry while shopping around here you'll find something for every taste and budget.

As you get past the multitude of eateries, there is CTV's headquarters at Queen and John. Around this spot you'll find cafés, bars and some great clothing and accessory shops (and a great bookstore). Some are vintage-style clothing stores with bargain prices, others are boutique-style with prices fit for celebrities. And there's a wash of everything in between.

When you move west towards Spadina, you'll find slightly less densely packed stores, everything from MAC, the Gap, Club Monaco, Lululemon , to the famous Silver Snail comic book store. Even cinema geeks who aren't comic book lovers may like this place for its novel products and knowledgeable (and fun) staff. During the summer, this is where you'll often find street vendors eager to barter over jewelery and accessories.

Past Spadina, things begin to taper off in terms of big box retail stores, but this is the part of Queen Street many people make long trips to get to. There are many textile shops, and a ton more clothing and specialty boutiques. Adults can head one block west past Bathurst  (no further than Palmerston Avenue ) for two "grown-up" stores that are reputable and friendly.

You can walk Queen Street right to the end if you have a full day and desire to see some of the most eclectic stores in Toronto ... note, though, that the walk itself (from University to the Queensway ) would take just over three hours! You may want to seek out your favourite types of stores and restaurants on Google Maps before heading out on your excursion.