The Disney influence is everywhere in the city that was reborn in 1955 with the opening of Disneyland. Formerly a sleepy suburban town, Anaheim today is a vibrant tourist center with fine dining, shopping, festivals, myriad attractions and a range of accommodations.

"When in Rome, do as the Romans." That classic advice leads to a wealth of options: Should you follow Augustus and Caesar, whose Rome is filled with spectacular ancient structures? Or Michelangelo and Da Vinci, whose city invites artistic pilgrimage? Maybe you'll discover the Rome that enchants lovers and sightseers alike? Rome encompasses all this and more.

Historic and modern, European and Asian — that's Istanbul. The city at the junction of two continents is home to ancient structures like the Hagia Sophia and the Blue Mosque in the Old City, as well as modern businesses, hotels, restaurants and nightlife in the New City.

Paphos, the capital of western Cyprus, has some serious historical clout. Site of the vast fourth-century BC Tombs of the Kings, set high on a cliff above the sparkling sea, as well as a dramatic Byzantine castle and fine mosaics, it's also known as the birthplace of the goddess Aphrodite.