"When in Rome, do as the Romans." That classic advice leads to a wealth of options: Should you follow Augustus and Caesar, whose Rome is filled with spectacular ancient structures? Or Michelangelo and Da Vinci, whose city invites artistic pilgrimage? Maybe you'll discover the Rome that enchants lovers and sightseers alike? Rome encompasses all this and more.

Coveted by empires and republics throughout its history, Innsbruck was the seat of the imperial court of Maximilian I by the end of the 15th century.

South Beach, or SoBe, is Miami Beach's buzziest bit. The vibrant area, with its pastel-hued buildings, hip nightclubs, trendy shops and see-and-be-seen restaurants, attracts socialites and their satellites year-round.

Where else are Ernest Hemingway and Jimmy Buffett equally revered? Key West is a sunny, fun destination with enough sights to keep you busy when you're not snorkeling, parasailing or catching some rays.