"When in Rome, do as the Romans." That classic advice leads to a wealth of options: Should you follow Augustus and Caesar, whose Rome is filled with spectacular ancient structures? Or Michelangelo and Da Vinci, whose city invites artistic pilgrimage? Maybe you'll discover the Rome that enchants lovers and sightseers alike? Rome encompasses all this and more.

Where else are Ernest Hemingway and Jimmy Buffett equally revered? Key West is a sunny, fun destination with enough sights to keep you busy when you're not snorkeling, parasailing or catching some rays.

The Algarve's sunny shores offer perfect escapes for all types, from those seeking the hot nightlife of flashy, energetic Lagos to those desiring secluded stays in rambling Sagres.

If watching the sunrise from atop a 10,000-foot volcano, swimming under waterfalls, hiking through craters and luxuriating on white-, red- and even black-sand beaches sounds like paradise, then Maui awaits.