"When in Rome, do as the Romans." That classic advice leads to a wealth of options: Should you follow Augustus and Caesar, whose Rome is filled with spectacular ancient structures? Or Michelangelo and Da Vinci, whose city invites artistic pilgrimage? Maybe you'll discover the Rome that enchants lovers and sightseers alike? Rome encompasses all this and more.

America's family fun capital, Orlando is home to Walt Disney World, Sea World and other famous mega-theme parks, including Discovery Cove and Universal Studios.

A beach-lover's paradise, this Caribbean island's interior boasts desert, but the coasts are filled with picture-perfect, powdery white sand and tranquil sapphire waters.

Historic and modern, European and Asian — that's Istanbul. The city at the junction of two continents is home to ancient structures like the Hagia Sophia and the Blue Mosque in the Old City, as well as modern businesses, hotels, restaurants and nightlife in the New City.