I booked a room in this hotel for five nights towards the end of September. It's a really cute little place and my attic room (35) was adorable - quite small, but very well furnished and with lots of nice touches throughout that give it a really unique atmosphere. The staff at the front desk were great, especially letting me check in early after a long drive up from Corpus Christi.
I do have a few small nitpicks: the room is reasonably priced (I booked through Expedia and got a discount because I was staying more than three nights), but there are a LOT of extra charges. You'll pay about $15 per night for self parking, there's no complimentary breakfast and the cheaper items on the room service menu are pushing $10. If you do order from room service, you'll also have a long wait for your meal. I found it easier to make a trip to a supermarket and stock up on food than to try to get anything in the hotel. As well as this, there is currently a massive construction project going on about 100 yards up the road and they did start work at about 6.30am every morning. Good luck if you want a lie in!
In terms of location, the hotel is less than a ten minute walk from downtown and the Alamo. However, it is situated at a point where the neighbourhood feels like it might be beginning to deteriorate - it's literally just outside the limits of the touristy part of the city. As a woman travelling alone, I felt confident enough to walk around there during the day, but I wasn't entirely comfortable with the thought of being out there by myself after dark.
For drivers, San Antonio is a massive pain to navigate because the whole of the downtown area is a one way system covered with roadworks. When you do eventually reach the hotel, it's quite easy to spot and has a reasonably large car park. However, you will have to pay to use it - I'm not entirely sure what the charge is for as it's self parking, but it'll automatically go on your bill and if you're there for a few night it soon adds up.
In summary, I did like this hotel and would definitely consider staying there again. I was just a little off put by the amount of money it cost for anything beyond a basic room.
Good points: quirky, within walking distance of downtown.
Bad points: expensive, paying for parking.