I arrived at the Hotel Marlowe pregnant and tired, and they couldn't have taken better care of me. They arranged a quiet room for me and even picked up my takeout order for dinner one night! I love the cucumber and fruit waters available in their lounge, and if I wasn't pregnant, I'd definitely take advantage of their nightly wine tastings. The room was spacious, stylish, and comfortable.
In response to a previous review: the hotel is located in East Cambridge, near the mall, MIT, the Science Museum, and a bunch of delicious restaurants (Helmand's, Catalyst, and more). If you'd prefer to be located near Harvard Square or other attractions, do your homework first -- don't blame the hotel!