If you are looking for a hotel to stay in Manhattan, choose Residence Inn. It is located between Lexington avenue and Third avenue very close to Grand Central.
The rooms are large, clean and equipped with everything one may need: fridge, cooker, tableware, hairdryer, etc.
The personnel is very efficient, polite and helpful.
In fact, I am fishing my memory to find anything I found annoying during my stay and fail. The only tip I may give: ask either for a room not facing 48th St, or for a room located the higher the better. I woke up 5:30 a.m. because of noise made by a trash collecting truck. Believe me, it was not a little five minute noise, it was a long symphony accurately performed during 40 minutes! However, that was the only inconvenience I had to struggle. In all other respects the hotel is two thumbs up.