Just came back from a very plasant 10 day New York trip with my girlfriend.
Our stay at the St. Marks Hotel was a real treat. We had a queen room at a very fair price (U$ 150) that was very clean with towels changed daily.
The only real problem with our specific room was that it faced the internal area of the building and the exhauster from the bar/restaurant downstairs would leave a very strong and unpleasant smell of greasy cooking throughout the entire room. Because of this, our only option was to keep the windows shut at all times with the AC on and even then some of the smell would eventualy come into the room, but no big deal. Maybe next time I'll request a room facing the street.
The staff was very professional and courteous, specially Sammi, who was always ready and happy to help our every need.
As everybody has already mentioned, there's no elevator, but I couldn't care less about that.
All in all, highly recommended and for the price, it's a no brainer!
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.