We just returned from our long weekend in NYC where we had a studio at the Stanton Street location. This really is a great option for seasoned travelers who don't expect many perks. You have a clean, safe, comfortable space to kick back in while in town. The rooms, while comfortable, are not without their qwerks. If you were not aware prior to your arrival, the Stanton location is essentially a set of second floor units located above a yoga studio. Remember that you're not booking a room at a hotel, but a studio above a functioning business. Outside of business hours, you're flying solo! The room itself was adequate for our needs. It's not perfect by any means, but then again, I'm willing to bet that your own home is not in perfect shape. We had some loose fixtures in the bathroom and the shower thermostat is plumbed backwards (red=cold, blue=hot). Likewise, the property is strictly vegetarian so you should not be using the kitchen to cook meat products. But then again, you're staying in the Lower East Side, a cultural and foodie gem. We never once used our kitchen other than heating water. The heating/cooling system was a little janky as well. We found it difficult to maintain a steady temp, but it was loud enough to drown out any city noise from outside.
It's about a 10 minute walk from the Delancey/Essex station which can easily get you just about anywhere you would want to go directly or with a single transfer. We arrived via JFK and took the AirTrain and J line all the way in without a problem.
When all is said and done, we would easily snag one of these studios if we found ourselves staying on the LES again in the future.