I've had the pleasure of staying at Sanctuary Guest Suites a number of times. What keeps bringing me back is the zen-like atmosphere, the accommodating staff, and the super comfy beds.
It also really nice to stay at place that gives back to their community the way Sanctuary does. They are involved with a program called Food For Life-- which feeds the homeless of NYC at Tompkins Square Park every Mon,Weds, &Fri. They encourage to come volunteer as well.
All in all: if you are looking for a nice welcoming accommodation with a wonderful staff-- this is the move for you!