I've stayed at Andaz quite a few times while on business, do this review is based on my experiences over last 3 yrs.
Location: great for Wall St, not so great for mid-town or Central Park area. Best location if you're on a business trip.
Rooms: on a smaller side, but very functional and convenient, unfortunately not very quiet. It's worth upgrading if you can. Proper large bath and walk in showers are great, beds are comfortable and firmer than in some other hotels. Radio/ I-phone dock is poor quality.
Facilities: both bar and restaurant are reasonably priced and good, and in my view got better over last yeat. Gym is ok, but currently closed (ask for a voucher to go to proper gym on Wall st).
Service: friendly and attentive, as almost always in good NY hotel, can't complain.
Although I stayed only on business, prices are reasonable and I would definitely consider staying over for the weekend as well.