I stayed here over the 4th of July holidays, and I was very impressed with the property relative to other Residence Inns and the location within the Gaslamp district is outstanding. Lots of things to see and do within walking distance of the hotel. It is only a few short blocks (maybe 5 minutes walking tops) to Petco Park. The ferry to Coronado Island is also within walking distance, and driving from the hotel to Coronado Island with no traffic is only 10-15 minutes.
I found the layout of a few rooms a bit awkward (like the TV behind the couch) and had to look at a few before I found a layout that fit my preferences, but the rooms are modern, very clean, and the beds are comfortable.
My overall rating of the hotel is very good, and I would recommend to others and stay here again myself... but I did have a few hiccups starting with the checkin. The staff did try to make it right but only after I raised the issues.