Though we only stayed in this hotel one night, we would definitely return when in Boston. The location is superb...two blocks from South Station in the heart of the Financial district. Very close to the Aquarium, North End, Fanuiel Hall and Haymarket Square.
The rooms are quite spacious, the bathroom huge with plenty of towels. We found it immaculately clean. The corridors have many twist and turns, so you could have difficulty finding your room, but they are very quiet.
The lobby is large, with two or three restaurants to choose from. There is a lovely area out back to sit and enjoy the sunny weather and great views of Boston Harbor.
I would highly recommend this hotel.

Excellent experience over all. Spotless, comfortable rooms. Great location. Terrific service.

I particularly enjoyed the fitness center. I am something of a connoisseur of hotel fitness centers, and this was one of the best around (slightly larger and more modern than Boston Harbor Hotel).

Modern hotel located conveniently near all amenities. Hotel staff were very welcoming and accommodating to allow for early check in when we arrived. Valet parking worked very well and was worth the $40. Would recommend staying at this hotel.

Great hotel, really comfy bed, good food with excellent waitresses in the bar area, very helpful staff all round. The location is really central, some might say a little pricey but I got a good deal and you nearly always get what you pay for with hotels.

I'd say highly recommended if you can afford it.