A trip to Asheville without a day at The Estate is a waste of a very fine day indeed. Go early and take time on your drive into the estate grounds to enjoy the work of famed landscape architect Frederick Law Olmstead, the creator of Central Park. You will be directed at the gate to a specific place to park. Some of the lots are walkable to the house (A and B) and some are a bit further afield but there are frequent buses that pick you up in the lot and drop you at The House. Be sure you note which lot you've left your vehicle in or it could be a very frustrating end to the day.
During the busier summer months, you may not be able to access The House immediately. You will receive a slip with a designated entrance time on it near the entrance with instructions to return at that hour. This small inconvenience prevents overcrowding in The House and is a sensible approach, so bear with the wait. It usually isn't very long. There are very nice shops and places to snack or enjoy a meal just to the right of the entrance and the walled garden and greenhouse are located to the left and down the stairs.
At the house, I highly suggest the audio tour which gives you highlights and explanations that illuminate the various rooms. These are quite interesting. The House is simply stunning. Hard to imagine one family enjoying that kind of wealth without royal origins.
Afterwards I suggest a visit to The Winery for a short tour. The Biltmore Company is now producing creditable wines, most of them imported from California and bottled at The Estate. The Bistro, located just outside of the winery, has excellent menus and there is a very casual outdoor cafe nearby as well. But for casual fare and a quick pub lunch, I suggest you venture around the corner to Antler Hill and enjoy a pint of Guinness at Cedric's. Food here is quite good. There are shops at Antler Hill and a farm implement museum just past Cedric's with a small outdoor theater that presents a short feature film about The Estate. There are two interesting demonstrations in the immediate area, a blacksmith's forge and a woodworking shop. Children and adults will find these demonstrations fun and enlightening. There is also a petting zoo just down the hill. The two draft horses are spectacular.
There is much to do at The Estate. There are walking paths along The French Broad River and bicycle and segway rentals and tours. There are rafting trips on the French Broad River and a variety of other outdoor activities. Even a drive through the estate grounds from Antler Hill is a beautiful route. The Outdoor Center is located at Antler Hill and can provide maps and information.
Above all, enjoy your day however it unfolds. Try to pick a good weather day and spend much of it outdoors after the tour of The House. For those uninterested in outdoor activities, venture up to The Inn at Biltmore just above the Winery for afternoon tea (pricey, mind you) or make a reservation for dinner (also pricey) there later, which is positively the best Asheville has to offer and worth every penny.
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.