This is the best hotel to stay in The City. It's right off the Muni so easy access to get back to the airport after your stay. Great location too as the Powell cable car is within walking distance to take you across town. My family and I always get rooms here when we go visit my brother. We love meeting in the wonderful rooftop lounge with beautiful city views for before dinner cocktails and appetizers before his jazz shows at Martunies bar (another great venue) down the street. Clean rooms, great lounges/restaurants and valet parking. Oh and for those who like Starbucks there is one in the lobby.
Expensive but worth every penny!