Our hotel of choice the past few visits to San Francisco has been the Handlery in Union Square. After trying out a couple other areas, we have found Union Square to be ideal for us: near to many museums, art galleries, fine restaurants, quaint neighborhoods (short walks to Chinatown, Nob Hill, North Beach, the Embarcadero, etc.). The rooms are decently appointed, but nothing special. We used the pool & the business center. The concierge was helpful. Main drawback was expensiveness. True, it IS summer tourist season, and we did stay on the weekend, but we never paid so much for a hotel....OR the parking. Considerably more than we paid in NYC on our 2 visits there this year. Would return here again, but not on a weekend.