After reading many reviews and suggestions on Trip Advisor on where to stay in San Francisco, we decided on the Best Western Tuscan Inn at Fisherman's Wharf. Many of the reviews said not to stay at Fisherman's Wharf because it is too "touristy" and that Union Square is much nicer. We loved this hotel and the Fisherman's Wharf area. We stayed here four nights, and we were maybe two blocks back from the main street of Fisherman's Wharf, but it was very quiet at night. When we would go through Union Square on the streetcar or whatever, I thought it was basically one big shopping area and was glad we didn't stay there.
This Best Western didn't offer breakfast like a lot of the other ones do so we ate at the Hollywood Cafe or IHOP in the mornings.
I'm glad we chose the Best Western and would stay here again if we come back to San Francisco. We had no problems getting around, and everyone at the hotel was very friendly and helpful.