My family and I stayed at the St. Regis in San Francisco for 6 days and 5 nights. We had a room with a city view on the 18th floor. Since I was traveling with my wife and my 2 boys, 8 and 11 years old we got a room with 2 queen size beds.

The Good: The service was outstanding and everyone tried to do whatever we needed, when asked. The staff was very helpful with directions and one time we needed a nail clipper and we called the butler service and 5 minutes later the clipper arrived with an emory board. We also called down for a DVD and we received "Escape from Alcatraz" in about 5 minutes after we called the butler.

The realistic: The rooms are beautiful, the beds are extremely comfortable and everything in the room is controlled electronically, black out curtains, drapes, lights, etc. The decor is contempory with neutral colors. The rooms were average size, although for SF they were probably larger than most. The pool was not yet open, so that was a little disappointing for my kids. Also, I did sense that everytime we walked through the lobby that some of the hotel staff were not that thrilled that we had our kids with us.
Location was great. Close to all of the things that we wanted to do in the city.

Overall: Outstanding hotel, great service, but probably not the 1st choice for a family. If you are traveling without the kids or on a business trip probably one of the nicest hotels in SF.