The Vitale is located on Mission Street directly across from the ferry dock. It's a great location, an easy walk or taxi ride to all the downtown attractions. Great restaurants within an easy walk. We stayed in a room looking out at the Bay Bridge and with all the beautiful lights, it's a wonderful vantage spot. Room was clean, hotel has a contemporary vibe; the patio bar was packed with locals, staff were very helpful and attentive. We would definitely return.