This hotel is a few minutes on the opposite side of town from the Villa Romana del Casale (in other words, it's a few minutes by car into town, a few minutes to go through town, then a few more minutes to get to the Villa). There is rarely someone at the front desk, and one generally has to phone the restaurant, and someone will come in to help. The staff are all quite nice, but none speaks a word of English.
Our room was on the ground floor, and there was no highway noise from that floor, as others have complained about. It may be a problem in higher floors. When entering the hallway, you kind of have to take a "leap of faith" into the darkness, because the lights only turn on after you enter the hallway (motion sensor). The rooms are clean and comfortable, but the TV's don't have a single channel in any language other than Italian.
The restaurant had a number of different items on the menu, and it gets quite full with locals after 9 PM, but I never saw anyone order anything but pizza. We did the same (the pizza was quite good). The breakfast was OK. Not among the best of our trip, but certainly quite adequate. Parking is easy and plentiful.
I might have rated this place more highly, but it advertises as a 4*, and it's nowhere near that by any stretch of the imagination. It hardly even qualifies as a 3*. There is nothing extra one might associate with a 4*, such as a pool, fitness center, or hot tub, and I don't see how a place with no front desk staff, no bilingual staff, and limited TV channel selection can call itself a 4*. The 3* we stayed for the next 4 days in Catania was significantly nicer (Hotel Mediterraneo). If I had to do it over again, we would have visited the Villa as a day trip from Catania or Palermo--the highway connections are quite good.
The ground floor rooms are quiet and you don't have to deal with the small, old elevator.
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This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.