I stop at the Harpoon Brewery every time I drive through Vermont. They have a nice galley with good bar food in a decent, casual setting. The beer is GREAT, though; fresh and right off the assembly line. Make sure to take a brewery tour for $5 in which you'll be treated to a number of excellent samplings. If you don't have to drive, enjoy a glass of Leviathan IPA -- one of the finest ales ever brewed.
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