I had a recent business/conference stay at Moody Gardens. This is a really nice location with a lot of amenities. For a location not billed as a 'resort' it has everything you could want on site, or very close by. I suggest looking at the website for more complete details. However, there's something for everyone from spas, to pools (indoor and outdoor), exhibits, watermarks and an aviation museum close by.
Conference facilities were more than adequate and the staff was very attentive. This is a place you can bring your family on business and not worry about them having to travel far to do anything.