My sister-in-law picked Shem Creek Inn for our hotel for our family vacation in Charleston. I arrived first and found out that our rooms weren't next to each other (not great when traveling with a 5 year old who likes to go between rooms). The staff was able to accommodate my request for the rooms to next to each other, even though they were close to full occupancy. The rooms were good sized and the AC definitely worked. I had a marsh view room, which was quiet and relaxing. All the staff was friendly and they were great to my niece.
The marsh walk next the Inn is a must do, especially at sunset. There are plenty of restaurants and bars in walking distance.
I would recommend Shem Creek Inn to anyone visiting in the area and would return there on another vacation.