My wife and I recently stayed for a weekend at the Sonesta Resort on Hilton Head Island. Neither of us had ever been to Hilton Head so we had to base our choice on all of the really positive reviews they already had. Sonesta is basically brand new after an extensive renovation within the last few years. Their pool is a superbly relaxing area with a bar and grill as well. We probably spent an entire day just reading, soaking, and counting our tan lines.
There are also plenty of extras you can partake in at the resort. Rental bikes, excursions, and lots of family friendly activities for kids. Plus a great spa and massage area upstairs which we both recommend.
Their food is also very well done at both of their main restaurants off the lobby.
Overall, we came back from our trip refreshed and ready for the rest of the year. They provided a much needed vacation.