I stayed at the Hampton Inn University Center last week for a work event that was in town and was very impressed with this hotel. My room was absolutely gorgeous and very clean. The entire staff was very nice and accommodating-- I had a light bulb out in my room and the maintenance guy came up to fix it within minutes of me telling the front desk.
The complimentary shuttle is convenient because the hotel is so close to other neighborhoods of the city like Southside and Station Square. The continental breakfast was wonderful as well.
I wish the other buildings in the area would be fixed up or torn down because when you first show up to this hotel, you get the impression that it's in a bad area, but that couldn't be further from the truth! I would definitely recommend anyone staying in the Pittsburgh area to stay here.