We randomly landed on this hotel due to a Hotwire bid on a downtown hotel. The room itself was quite nice, aside from a strange sink/shower/toilet 'all in one' bathroom with very little counter space. We didn't eat in the restaurant but it had a great atmosphere, as did the hotel's public areas. The location was just fine and very close to multiple public transportation options. Perhaps not as 'happening' of a neighborhood as the Pearl District, but a quick hop, skip, and a jump from everywhere we wanted to go.
What made this hotel an exceptional experience, for us, was the phenomenal staff. Every single person we spoke to at the front desk was knowledgeable, enthusiastic, and seemed to truly enjoy sharing their city with us through their thoughtful recommendations. If I needed to hire a team to work at my hotel (okay, I don't have a hotel ... but hypothetically), this would be the one.