Stayed 5 days in the Wynn; our room was a double king. Magnificient view (panoramic) on the 58th floor. Our room had view on the mountains (no strip view), and due to this we had noise in the night from the XS club (the club is located on ground floor between encore & wynn, when you are facing the rear side of the wynn this area is close to you). But it wasn't a problem for us.
Super room size, very clean, no cigarette smell/smoke. Just to nag, Maybe the shower could have a raindance or other showerhead instead of the standard one (for a 5* this could be a extra). No coffee/tea infrastructure, should be included in a 5*
Superb casino floor, definitely the most cosy & stylish casino in Vegas. Table limits are on the higher segment (eg. BJ 25$),but this is pretty normal for this style of casino.
If you are playing be sure to "claim" a waitress the first second you are playing, otherwise you could end up waiting pretty long for somebody to pass by. Alcohol level in the drinks are low, compared to the drinks served at the bar or the night clubs. (but hey they are free, compared to the $16 you might pay otherwise)
FYI Enough pools to visit, encore pools are visitable by Wynn people by just showing your badge. I found this information hard to find on tripadvisor.
Excellent hospitality, very friendly and professional, but clearly NO overacting. Be sure to constantly check the rates before arriving, our rate was adjusted 3 times in our advantage. But you have to ask for it.
Big carpark, car spots are suitable for any type of car. Be sure to go the level +1 for easy entry to the Wynn (no stairs hopping)
Food prices in the hotel restaurants are pretty high. Although it didn't bother me. You might get comped when playing (we did). I recommend visiting The buffet, just the sushi is a no-no. Fashion Mall is just at the other side of the street. The location of the wynn is NOT central, rather the "end" of the strip.
If you stayed at the Wynn, i'm pretty sure you won't accept anything else in Vegas.