I stayed here for one night last week. Very easy to find from I-10 to 1-110 without difficulty, in fact it looked like all the properties in the area are as easy to access. I was offered a choice of room location and I chose a higher floor, which turned out to have a nice view of the back bay. The room itself was nice, not exceptional of itself, but it had everything necessary to make my stay comfortable and pleasant: plenty of hot water w/good water pressure in the shower, nice coffeemaker with regular coffee and half and half (not powdered stuff), real cups and glasses, comfortable bed and pillows, lots of towels, good hairdryer. Of course these are things we take for granted, and all little things on their own, but having them available without asking goes a long way to making a difference. There was no odor of smoke in the room as others have mentioned, perhaps due to the higher floor. The room and the corridor also seemed quiet, perhaps for the same reason, since there were definitely a lot of people and a lot of kids staying there over the holiday.
I was here to see a concert, so did not spend much time at all in the casino, but I had a bit of spare time and walked through out of curiousity. There are casinos on both the first and second floors. Not surprisingly, the smoking areas seem to have a lot more activity than the non-smoking area, but the ventilation seemed good enough that the smoke was not overwhelming or hanging in the air.
The only restaurant I ate in was Highlights, the sports bar. The menu offered a good variety of bar food and had a good selection of beers. Prices are moderate but the portions are generous. I had a burger which was huge and cooked perfectly to order. Other diners meals also looked good. David, one of the 2 bartenders/servers makes you feel at home. It was very busy, yet he stayed on top of everything efficiently and kept everything humming without losing his sense of humor yet still had time to be extremely pleasant and chat with everyone for a moment or 2.
Next time I travel to Biloxi I'd gladly stay here again for more than one night and see more of the area.
Higher floors have a nicer view of the water. Rooms on the 28th floor did not smell smoky.
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This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.