We stayed at this hotel for 5 nights for a recent Mayo visit and I was very happy with the room (especially the extra space the studio suite provides - very nice for an extended stay) and found it to be a great value compared to the other two hotels we stayed at during previous visits (which were also nice but more expensive). This is a little outside downtown but was only a 10 minute drive to Mayo clinics (there is also a free shuttle but we chose to drive).
Although the parking lot was fairly full we never heard any noise from other rooms but we were staying there Sunday through Thursday nights so I'm not sure what the weekends were like. Checked out the hot tub and only saw one other family there. The breakfast was very good and they rotate the hot selections each day between 3 or 4 different items. The bed was comfortable and was able to get a lot of work done at the desk. Staff was very nice and helpful.
The only complaint I would have is that they don't have a safe in the room.