We chose the Comfort Inn in Plymouth due to its proximity to Interstates 275/94/96 and easy access to Ann Arbor and downtown Detroit (we were in town over a weekend to catch a Michigan Wolverines and a Detroit Lions game).
The hotel is clean with decent sized rooms and a large lobby area. It also has a small business center with a computer and printer. While our room was quite comfortable it did have a slightly smoky smell to it. My understanding is that the rooms are being renovated - not clear ours had been done yet (it definitely was a little dated in its look). As with all Comfort Inns, a hot breakfast was included. We appreciated there were lighter items such as yogurt to the usual donuts, bagels, scrambled eggs and sausages.
The staff were extremely friendly, greeting us every time we came into and left the hotel. Our room attendant even asked if we wanted our sheets changed.
While there are few choices nearby to dine out at (apart from your typical fast food joints) it is a short drive to downtown Plymouth where there are some great options (see my review on Fiamma Grill). It's also a relatively short drive to some decent shopping.
The Comfort Inn Plymouth is a good option if you're looking for something inexpensive in the western suburbs of Detroit.