My boyfriend and I decided last-minute on a post-Valentine's day getaway to Portland from Boston and luckily the Residence Inn had one room left. Upon arrival we noticed how close the hotel is to the Shipyard Brewery (tour wasn't the best we've had, but they give out plenty of free samples!) and the ocean (not nearly as enjoyable in February as in the summertime). It is, however, about a 10 minute walk from most Old Port restaurants and shops - quick, but not as centrally located as a few of the other top-rated picks on TripAdvisor.
Service at the hotel was phenomenal. From the man checking us in who joked about most incidental charges being related to the abundance of Portland brewpubs, to the ladies at breakfast who offered to clear our tables, we felt thoroughly welcomed.
The hotel itself is very new and clean. We had a "studio suite" which was bigger than most standard rooms. The rooms are set up for extended stays with full kitchens, making me wish we were staying long enough to cook anything (although I doubt we would've given Portland's foodie scene). We also took advantage of the pool and hot tub (nice but not huge) and the gym (brand new equipment, most with televisions. 3 treadmills, 3 ellipticals, a stairstepper, free weights, etc.).
The included continental breakfast was better than most, but not as expansive as some others I've seen. Think parfaits, fruits, cereals, bagels, pancakes, scrambled eggs, hash, oatmeal, etc.
Overall great stay!