I've now stayed at this Hampton Inn three times - all overnights before early morning flights. It's new, clean and comfortable. Staff are friendly. Rooms are spacious, with good climate control and very comfortable beds. The king rooms with only a shower seem to be the "new" Hampton design with the bed not against the wall adjoining the next room which I really like - keeps it more quiet when sleeping. Bathrooms are clean. Free parking and wifi.
My only "complaint" would be that you will hear planes starting at about 3:30am as the Fed Ex cargo flights begin at that time. I can't speak to when they stop taking off as I usually am leaving by 5:30am to catch a very early morning flight. They are loud enough that I could even hear them while in the shower. Since it is an airport hotel though, I wasn't surprised or bothered by the noise. Oh, and the elevator always smells like diesel for some reason.
My first choice near IND. I'll definitely be back.